Liverpool have a lot of work to do on Wednesday night at Anfield, a stadium that may not have the mystique of yesteryear due to COVID-19 restrictions. The Reds go into the second leg of their Champions quarterfinal tie versus Real Madrid after a 3-1 loss in the first leg. Liverpool must score twice without reply to go through to the final four of the competition. If Real Madrid get on the scoresheet, which they did three times in the first leg, then the mountain Liverpool must climb gets even larger.

Real Madrid head into the game on a high after defeating Barcelona 2-1 in El Clasico. The victory takes Real Madrid into second place and one point back of capital rival Atletico Madrid. We are not sure what is more shocking, Atletico Madrid’s once 10-point lead being down to one or that there is a three-team race for the league title in Spain.

Liverpool have won four of their last five games in all competitions. That run of form includes a 2-1 come from behind win at Anfield against Aston Villa at the weekend. Mohamed Salah and Trent Alexander-Arnold got onto the scoresheet for the Reds after they went into the halftime break down 1-0. The victory took Liverpool into sixth place in the league. They are three points off of the top four, but the only way they may achieve Champions League football for next season is to win the competition this term.

Real Madrid are in great form, unbeaten in 13 straight games in all competitions. The Reds need another magical Champions League Anfield night to progress to the semifinals.

Liverpool vs Real Madrid Odds


Cast your mind back to the 2018-19 Champions League when Liverpool went into semifinal second leg against Barcelona down 3-0. The Reds didn’t have Salah or Roberto Firmino on the night, yet achieved the most remarkable comeback in Champions League history – outside of the 2006 final in which Rafa Benitez’s Reds fought back to defeat AC Milan.

On Wednesday night, Jurgen Klopp will have both Salah and Firmino, but needs the two to show up – unlike the first leg. Yes, Salah got the Reds’ only goal, but he had little impact on the game. The same could be said about Sadio Mane, who was dropped for the win versus Aston Villa. The out of form forward could be left on the bench at the start once more.

Leading sportsbooks have Liverpool at odds of 1/1 to win the match at Anfield. That doesn’t mean they will progress to the next round. A goal for Real Madrid changes everything. Despite being favourites to win the match, Liverpool are underdogs to progress to the semifinals. They are at odds of 17/5 to reach the semifinals.

Real Madrid are at odds of ¼ to qualify for the semifinals. They are underdogs to win the match, however. They are at odds of 11/4 to win the game away from home. Los Blancos’ last trip to Anfield was in the 2014-15 Champions League group stage. They left Merseyside that night with a 3-0 win.

Liverpool vs Real Madrid Team News

Liverpool desperately missed captain Jordan Henderson in the first leg. His leadership in midfield was a big miss. He is set to miss the second leg but could return by the end of the month. Joel Matip, Virgil van Dijk and Joe Gomez also remains sidelined with injury. Nat Phillips and Ozan Kabak are likely to return to the centre of defence despite the errors they made in the first leg. Fabinho could be inserted at the back, but it would weaken the midfield.

Curtis Jones could miss the match after suffering a muscle injury. Divock Origi is also ruled out following a muscle injury. Klopp’s big dilemma is whether to start Firmino, Salah, and Mane or Diogo Jota in place of one of the three players. Jota has been excellent for the Reds and could take Mane’s place after the latter’s indifferent performance.

Zinedine Zidane is without Lucas Vazquez after the winger/full-back suffered a season-ending ACL injury. With captain Sergio Ramos set to miss the game, Vazquez’s absence could weaken the defence further. Fede Valverde could miss the match after picking up an injury in El Clasico. Marco Asensio, who scored in the first leg, was rested by Zidane at the weekend. Meanwhile, Karim Benzema scored a spectacular backheeled goal versus Barcelona.

Making Zidane’s defensive worries worse are the possible absences of Dani Carvajal, and Raphael Varane. The former has a thigh injury and the latter is overcoming a positive COVID-19 test.

Liverpool vs Real Madrid Predictions

Both teams to score: YES @8/13 - BET NOW


The first leg was wide open with Real Madrid looking likely to score with every attack. Liverpool’s midfield struggled to slow down the Spanish champions while Kabak and Phillips looked slow chasing Real Madrid’s forwards. The Reds did get on the scoresheet through Salah. It is assumed Liverpool will start the game on the front foot and go after Real Madrid.

Mohamed Salah to score anytime @10/11 - BET NOW


Salah has 28 goals in 43 matches in all competitions, including the Reds’ only goal in the first leg. Salah has to step up for Liverpool, something he doesn’t always do in the big games. It is easy to forget that the winger was injured in that remarkable 4-0 win over Barcelona two seasons ago. Salah has scored in his last three games in all competitions.

Over 2.5 goals scored @4/6 - BET NOW


Liverpool have to score at least two goals to overturn Real Madrid’s lead. They also mustn’t concede to Los Blancos while scoring those two goals. Real Madrid are in great form and are hunting down Atletico Madrid at the top of the La Liga table. A goal for the visitors would change the complexion of the tie and force Liverpool to score four goals to go through. For every away goal Real Madrid score, Liverpool will need to score twice.

Liverpool may win the battle on Wednesday night, but ultimately lose the war to Real Madrid. They have massive mountain to climb. With the team’s decline this season, it may be an unassailable mountain.

Liverpool vs Real Madrid Tips 

Here are our Liverpool vs Real Madrid tips for Wednesday's game at Anfield. 

  1. Both teams to score: YES @8/13 - BET NOW
  2. Mohamed Salah to score anytime @10/11 - BET NOW
  3. Over 2.5 goals scored @4/6 - BET NOW