Manchester City kickstart their Champions League 2021-22 group stage campaign on Wednesday night at the Etihad Stadium against Bundesliga squad RB Leipzig. The Cityzens were the beaten finalists in the Champions League last season. Chelsea claimed a 1-0 win in the final. Pep Guardiola is aiming to get the team back to the final and lift the Champions League trophy for the first time.

Manchester City vs RB Leipzig Match Preview

First up for Manchester City are RB Leipzig, last season’s Bundesliga runners up. Having lost coach Julian Nagelsmann in the summer, centre-back Dayot Upamecano, and captain Marcel Sabitzer all to Bayern Munich, RB Leipzig have started the season in a very poor state. New coach Jesse Marsch’s team have lost three of their opening four games. On Saturday, RB Leipzig lost 4-1 to Bayern Munich at home.

Guardiola and company will be licking their lips ahead of the game on Wednesday. The Germans have conceded six times in four Bundesliga games. Manchester City are coming off of a hard-fought 1-0 win against Leicester City away in the Premier League. It was a game in which Manchester City nearly met their match, but were able to hold on for the victory. Now, Guardiola will be hopeful the Cityzens can start the Champions League on the right foot.

Manchester City vs RB Leipzig Betting Odds



Manchester City and RB Leipzig are joined by Paris Saint-Germain and Club Brugge in Champions League Group A. On the face of it, Manchester City and Paris Saint-Germain will be expected to finish in the top two to progress to the Champions League knockout stage. RB Leipzig and Club Brugge are expected to fight for third and a place in the Europa League post-Christmas.


RB Leipzig have reached the knockout stages of the Champions League in each of the last two years. Last season, after an up and down group stage campaign under Nagelsmann, RB Leipzig’s 3-2 win over Manchester United on the final matchday of the group stage sent them through at the expense of the Red Devils.

Leading bookies have RB Leipzig at the best betting odds of 19/2 to win at full-time against Man City. It would be a shock result for Die Roten Bullen. Manchester City are at the best betting odds of 8/25 to win at full-time against the German team.

Group A may be the most difficult group Manchester City have experienced for several seasons. It won’t be an easy group to top with the potential of Paris Saint-Germain.

Manchester City vs RB Leipzig Team News

Guardiola has a few injury and fitness issues going into the game on Wednesday at home against RB Leipzig. Back-up goalkeeper Zack Steffen is ruled out after testing positive for coronavirus. Benjamin Mendy is suspended by the club due to a pending sexual assault case. Liam Delap is ruled out with an unidentified injury.

Phil Foden and Kevin De Bruyne should play from the start. Meanwhile, attacking midfielder Bernardo Silva could earn a starting place in the XI after scoring the winner against Leicester City. The Cityzens dominated the game against Leicester City with 25 total shots and 61% possession.

Guardiola could bring Raheem Sterling back into the starting XI. He has preferred to play Jack Grealish on the left side of an attacking three. Ferran Torres is likely to start down the middle.

Marsch has got to unlock the team’s dormant attack. Summer signing Andre Silva has just one goal in four games after bagging 28 Bundesliga goals for Eintracht Frankfurt last season. Defender Marcel Halstenberg is a doubt due to an ankle injury. The team’s defence has given up six goals in four league games. The switch from a back three to a back four hasn’t worked well.

Manchester City vs RB Leipzig H2H

Wednesday’s match is the first ever meeting between Manchester City and RB Leipzig. This year’s Champions League is throwing up some new and exciting ties. This is one of those exciting ties. However, Nagelsmann’s departure from Leipzig and the loss of Upamecano, Ibrahima Konate, and Sabitzer gives the head-to-head advantage to Manchester City.

Even with the former coach and players, Manchester City would be expected to win this week. RB Leipzig’s last trip to Manchester wasn’t a good one. Last season, RB Leipzig played Manchester United in the Champions League group stage at Old Trafford. The Red Devils won 5-0.

Manchester City vs RB Leipzig Prediction

Both teams to score: NO @ 10/11 - BET NOW



Based on RB Leipzig’s form, our betting tips prediction is for both teams not to score and likely, Man City winning to nil. RB Leipzig have seen four of their five games in 2021-22 in all competitions finish with both teams not scoring. All four of Manchester City’s matches this season have finished with both teams not finding the back of the net.


Ferran Torres to score anytime @ 13/10 - BET NOW



Ferran Torres should lead the line for Manchester City against RB Leipzig. With Man City unable to land Harry Kane in the transfer market, Guardiola has turned to Torres to play as the team’s central striker. Torres has two goals in four Premier League matches in 2021-22. Our betting tips prediction is for Torres to score anytime.


Over 2.5 goals scored @ 13/25 - BET NOW



There is the sneaking suspicion that RB Leipzig could get blown away on Wednesday night. This is not the RB Leipzig we have seen over the last few seasons. They are in a rebuilding mode under Marsch. Three of RB Leipzig’s five matches in all competitions this season have finished with over 2.5 goals scored. Two of Bayern Munich’s four matches in all competitions ended with over 2.5 goals tallied.


Manchester City should claim a win on Wednesday night against RB Leipzig. Although Manchester City may not top the group and face a difficult last 16 opponent, they shouldn’t have any difficulty with RB Leipzig at home. Leipzig’s 5-0 loss to Manchester United in last season's groups stage will be fresh in their minds. Can Man City replicate it?