Fresh off of a 5-0 win at Old Trafford against Manchester United, Liverpool head to Deepdale for the fourth round of the Carabao Cup. Liverpool reached the fourth round of the competition thanks to a 3-0 win over Norwich City.

Preston vs Liverpool Match Preview

Jurgen Klopp will need to make several changes to the team that started against Manchester United at the weekend due to injuries. James Milner and Naby Keita both came off the pitch during the game while Fabinho was unable to play from the start.

The last time Preston North End hosted Liverpool in a competitive fixture it was the FA Cup 2008-09. The Lilywhites lost the fixture 2-0 at Deepdale. Frankie McAvoy is in his first full season at Preston North End after taking over for Alex Neil in May 2021. McAvoy is in a rebuilding season at Preston North End. Currently the team is 19th in the Championship table, which is six points above the relegation zone.

Liverpool are currently the only Premier League team not to suffer a defeat in all competitions this season. The Reds are a perfect 10W-3D-0L in 13 matches in all competitions this term. The squad is strong from top to bottom and even with changes made for Preston North End, Klopp will expect safe passage to the quarterfinals.

Preston North End vs Liverpool Betting Odds

While Liverpool enter the Carabao Cup in the third round, Preston North End have already played three times in the competition. The Lilywhites defeated Mansfield Town 3-0, Morecambe 4-2, and Cheltenham Town 4-1. All three lower league opponents gave Preston North End a challenge for the most part. However, their encounter with Liverpool will be something completely different.

Liverpool have been brilliant away from Anfield this season. In eight matches, they won seven games and drew once. Liverpool have scored 30 goals on the road while conceding a mere six. Confidence will be through the roof following their 5-0 win over Manchester United.

Leading bookies’ best betting odds on a Preston North End shock win over Liverpool in the Carabao Cup fourth round are at 15/2. Liverpool are at the best betting odds of 4/11 to win the game at full-time away at Deepdale.

The only recent fixture between these teams was in the 2008-09 FA Cup. Liverpool won easily 2-0 with goals in both halves. Albert Riera and Fernando Torres scored the goals. Those names point to a completely different era of Liverpool football. Preston North End and Liverpool are at the best betting odds of 9/2 to draw at full-time.

Preston North End vs Liverpool Team News

Fabinho was a late withdrawal from Liverpool’s game at Old Trafford on Sunday. Despite being an indispensable player, Liverpool’s midfield three of Milner, Keita, and Jordan Henderson thrived. Fabinho is highly unlikely to play as Liverpool’s medical staff get him back to fitness for next week’s Champions League game versus Atletico Madrid.

There is a crisis in midfield going into Wednesday’s game which could see Henderson play once more. Milner, Keita, Thiago, Fabinho, and Harvey Elliott are all out. Keita’s injury is the most serious of the fresh issues. Paul Pogba’s horror tackle on Keita saw the Liverpool man stretchered off.

Henderson, Alex Oxlade-Chamberlain, Curtis Jones, and Tyler Morton will all be in line to play on Wednesday. Of the four, Henderson is the most need of a rest. Takumi Minamino can also step into the midfield three to play. He scored twice against Norwich City in the third round. Divock Origi also scored in the third round and should play from the start. Joel Matip was rested against Man United but could partner Joe Gomez in central defence.

At the moment Caoimhin Kelleher looks unlikely to play due to illness, which will give Adrian a rare start. McAvoy’s Preston North End has four players on the injury list. Ched Evans, Connor Wickham, Isaiah Brown, and Matt Osbourne are all ruled out due to injuries.

Preston North End vs Liverpool H2H

Games between Preston North End and Liverpool have been few and far between due to the teams being in different divisions. Liverpool won 2-0 when these teams met in the 2008-09 FA Cup. Two more games have been played between these teams since then, but both matches were friendlies.

Liverpool won those two friendlies as well. Preston North End have posted a home record of 4W-3D-1L in all competitions. They have won just once in their last six games in all competition, however.

Preston North End vs Liverpool Prediction

Divock Origi to score anytime @ 17/10 - BET NOW

Divock Origi isn’t getting a lot of time on the pitch this season due to the insane form of Sadio Mane, Diogo Jota, Roberto Firmino, and Mohamed Salah. He will play in the Carabao Cup and have the chance to score goals. He scored in Liverpool’s 3-0 third-round win over Norwich City. Origi will lead the line and our betting tips prediction is for Origi to score anytime.

Liverpool to win both halves @ 2/1 - BET NOW

In eight of Liverpool’s 13 games in all competitions, the Reds have won both halves. They throttled Manchester United at Old Trafford scoring four goals in the first half then one in the second period. Preston North End’s focus shouldn’t be on winning in the Carabao Cup fourth round. They should be more focused on not being relegated to League One. Our betting tips prediction is for Liverpool to win both halves.

Over 3.5 goals @ 4/6 - BET NOW

Six of Liverpool’s 13 games this season finished with over 3.5 goals scored. Each of Liverpool’s last six games in all competitions finished with more than 3.5 goals tallied. Ten of the Reds’ games in all competitions had at least 3.0 goals scored. They average 3.15 goals scored this season and concede an average of 0.85 goals per game in all competitions.

Our betting tips prediction is for Liverpool to win the game on Wednesday night versus Preston North End and the match to finish with over 3.5 goals scored.