Bayer Leverkusen vs Mainz 05 Betting Odds, Tips, Predictions, Preview 28th February 2026

When Mainz 05 come to BayArena for the Bundesliga match this coming Saturday, Bayer Leverkusen will be hoping to use their home advantage to their advantage.
Ranked as number 6 in the Bundesliga standings, Bayer Leverkusen, have so far collected 39 points this season, while Mainz 05 collected 22 points. This puts them up as number 13 after 23 rounds.
Bayer Leverkusen took down Mainz 05 in their most recent meeting, and bookmakers deem another win for the home side a likely scenario on Saturday.
Bayer Leverkusen are relatively average in the art of goal-scoring these days. They scored a steady 15 goals in their previous ten matches, for an average of 1.5 per game. They simultaneously allowed their opponents 11 goals, or an average of 1.1 a game. Furthermore, they fought their way to three clean sheets in this run.
Mainz 05 managed a bearable 15 goals from their past ten games, creating an average of 1.5 goals per game. They conceded 14 goals in total, and while claiming two clean sheets, they conceded 1.4 goals an average per game.
Supporters will be hoping to see a similarly thrilling encounter, as it turned out to be the last time Bayer Leverkusen played against Mainz 05. It finished 3-4 in a great match between the pair.
Bayer Leverkusen vs Mainz 05 Prediction
Bayer Leverkusen Form
In has been a bit of everything for Bayer Leverkusen in their previous three matches, where they first beat Olympiacos by 0-2. This was followed by a disappointing 1-0 defeat against Union Berlin, before an encounter with Olympiacos produced a 0-0 draw. Bayer Leverkusen managed a strong return of four wins from their previous six matches on home soil in the Bundesliga. They drew none though, while losing twice in this series. They scored 15 goals and conceded six times.
Mainz 05 Form
In has been a bit of everything for Mainz 05 in their previous three matches, as they first beat Augsburg by 2-0. This was followed by a disappointing 4-0 defeat against Borussia Dortmund, before an encounter with Hamburger SV produced a 1-1 draw. Mainz 05 claimed just one win from the last six away games in the Bundesliga. They also drew two and were defeated three times, as they were outscored by 15 goals to seven.
Head-to-head encounters tend to bring out the best in both sides, and we fully expect the trend to continue, when Bayer Leverkusen renew Mainz 05 their acquaintance.
Bayer Leverkusen took 24 points from their last 11 encounters with teams from the bottom half of the Bundesliga table. This amounts to seven wins after scoring 27 times and conceding 12. Mainz 05 fought their way to one wins and five points from their last eight games against teams inside the top six. They were on target nine times in these matches, but also let in 17 goals. Bayer Leverkusen have a record of 12 wins, three draws and seven defeats in the Bundesliga this season. Mainz 05 enjoy a record of five wins, seven draws and 11 defeats in the Bundesliga.
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Bayer Leverkusen vs Mainz 05 Stats
- Bayer Leverkusen have won the last 3 home matches in a row while scoring more than 2.5 goals
- In 7 of the last 9 Bayer Leverkusen home matches the sum of goals was over 2.5
- In 8 of the last 10 Bayer Leverkusen matches the sum of goals was under 3.5
- Bayer Leverkusen have won the last 3 home matches in a row and the sum of goals was over 2.5
- Bayer Leverkusen have won the last 3 home matches in a row while scoring more than 1.5 goals
- In 11 of the last 13 Mainz 05 away matches in the Bundesliga, the sum of goals was over 2.5
- In the last 5 Mainz 05 away matches the sum of goals was over 2.5
- In 6 of the last 8 Mainz 05 matches the sum of goals was over 2.5
- In 6 of the last 8 Mainz 05 matches in the Bundesliga, the sum of goals was over 2.5
- In 5 of the last 7 Mainz 05 matches the sum of goals was under 3.5
Bayer Leverkusen vs Mainz 05 Squads
Bayer Leverkusen Squad
Kasper Hjulmand will choose the starting lineup for the upcoming game against Mainz 05 from the players listed below (the information in the brackets refers to goals scored and matches played in the Bundesliga this season):
Janis Blaswich (0/6), Jesper Schlich (0/0), Jonas Omlin (0/0), Mark Flekken (0/17), Niklas Lomb (0/0), Alejandro Grimaldo (5/18), Arthur (1/15), Axel Tape-Kobrissa (0/5), Edmond Tapsoba (4/18), Issa Traore (0/0), Jarell Quansah (2/18), Loic Bade (0/19), Lucas Vazquez (1/9), Tim Oermann (0/0), Aleix Garcia (1/22), Equi Fernandez (0/12), Exequiel Palacios (0/6), Ibrahim Maza (2/16), Jonas Hofmann (2/19), Malik Tillman (4/18), Nathan Tella (0/10), Robert Andrich (1/21), Christian Kofane (3/19), Eliesse Ben Seghir (0/7), Ernest Poku (5/20), Martin Terrier (3/13), Montrell Culbreath (1/1), Patrik Schick (7/18).
Mainz 05 Squad
Listed below is the full squad of Mainz 05 players that the manager Urs Fischer will choose from for the upcoming game:
Daniel Batz (0/11), Lasse Riess (0/4), Robin Zentner (0/9), Andreas Hanche-Olsen (0/13), Anthony Caci (0/4), Danny da Costa (1/23), Kacper Potulski (1/9), Lennard Maloney (0/14), Maxim Dal (0/0), Maxim Leitsch (0/0), Phillipp Mwene (0/18), Silvan Widmer (2/17), Stefan Bell (2/18), Stefan Posch (0/5), Daniel Gleiber (0/0), Dominik Kohr (1/18), Jae-Sung Lee (2/21), Jeremiah Debrah (0/0), Kaishu Sano (1/23), Nadiem Amiri (10/20), Niklas Tauer (0/0), Nikolas Veratschnig (0/14), Sota Kawasaki (0/6), Armindo Sieb (2/15), Benedict Hollerbach (1/14), Fabio Moreno Fell (0/0), Kasey Bos (0/0), Nelson Weiper (0/15), Paul Nebel (1/19), Phillip Tietz (2/18), Sheraldo Becker (0/0), Silas Katompa Mvumpa (1/6), William Boeving (0/6).
Bayer Leverkusen vs Mainz 05 Team News
Mainz 05 face a list of four absentees from the squad ahead of their next match this coming Saturday against Bayer Leverkusen. Dominik Kohr, Phillipp Mwene and Sheraldo Becker racked up too many penalty points and won't be in the Mainz 05 travelling party for their next match.
Sheraldo Becker is too injured to face Mainz 05.
Bayer Leverkusen vs Mainz 05 Lineups
Bayer Leverkusen vs Mainz 05 H2H
Their latest encounter was a belter of a game, which finished with a 3-4 scoreline. An uncommon result, but we would not mind a similar goal fest this coming Saturday. Bayer Leverkusen were a little more successful than Mainz 05 in recent meetings, and go into their next encounter with a 6-2-2 advantage. Naturally, betting on Bayer Leverkusen has more often than not proved the profitable way to go. The bookies best betting odds on a home win are at 2/3.
Bayer Leverkusen vs Mainz 05 Results
Entertainment seems close to guaranteed when Bayer Leverkusen welcome Mainz 05 as over 2.5 goals came out a winning bet eight times in ten matches. Over 2.5 goals is best priced at odds of 2/3 with the bookies on Saturday.
Bayer Leverkusen vs Mainz 05 Betting Tips
Having scored just once lately in the Bundesliga, Lucas Vazquez will be eager to hit the target again, and the upcoming game presents an opportunity to step up. Mainz 05 hope Nadiem Amiri can inflict some damage on their upcoming opponents by adding to his tally of five Bundesliga goals in his last six Bundesliga games.
In their last 10 matches at BayArena across all tournaments Bayer Leverkusen won six times, drew two and lost two times. Mainz 05 claimed one wins, three draw and six defeats in their last 10 games away. Bayer Leverkusen are no doubt looking for goals on Saturday, since Mainz 05 have been unable to keep a clean sheet in their last 10 away games. The former fought their way to seven clean sheets in their last 10 games on home soil.
Both teams to score was a winning bet six times in the last ten encounters between these two rivals, while at least four goals happened five times. Bayer Leverkusen managed an average of 2.2 goals, while Mainz 05 averaged 1.4 goals a game. Bayer Leverkusen saw over 2.5 goals in four of their last ten matches across all tournaments, as they scored an average of 1.7 goals during this run. Of the last ten games for Mainz 05, six had more than 2.5 goals, while they managed to score an average of 1.5 times goals per game.