Bayer Leverkusen vs RB Leipzig Betting Odds, Tips, Predictions, Preview 20th September 2026

RB Leipzig head over to the BayArena this coming Sunday to face title favourites Bayer Leverkusen in a round 4 match in the Bundesliga.
A glance at the Bundesliga table reveals that the current difference between the teams is two points and two places.
Bayer Leverkusen find themselves as number 7 in the league table with four points from their initial three matches this campaign. As number 5, two points above them, RB Leipzig have played three rounds this season.
Bayer Leverkusen came away with three points from the latest encounter with RB Leipzig. It would be a surprise if they fail do to it again, when they face each other on Sunday.
Bayer Leverkusen are confident they will be scoring goals in their next assignment in the Bundesliga, as they show off very admirable numbers from their past ten matches. The hosts scored 2.4 goals on average per match, or 24 goals in total, while allowing 16 goals against, for an average of 1.6 per outing. They managed two clean sheets along the way.
RB Leipzig scored 22 goals, conceded 15 and held on for a clean sheet in three of their last ten matches.
Bayer Leverkusen had a good reading on RB Leipzig in their last two meetings, which they won by 3-1 and 4-1, respectively.
Bayer Leverkusen vs RB Leipzig Prediction
Bayer Leverkusen Form
Bayer Leverkusen look good before their upcoming match, in which they seek to remain unbeaten. In their last three matches, they first beat Union Berlin by 4-0, before drawing 2-2 with Augsburg. They were back as winners last time out, when they took out NK Celje 2-0. Bayer Leverkusen claimed a middle-of-the-road three wins in their previous six matches on home soil in the Bundesliga. They also drew two and lost one, as they scored 17 and conceded eight goals.
RB Leipzig Form
RB Leipzig suffered a couple of disappointments in their last three matches as they were run over by Werder Bremen in a 3-1 defeat. Como also proved too hard to handle as they won 4-1, before RB Leipzig were able to strike back in a 5-0 win against Hamburger SV. In their last six away matches in the Bundesliga, RB Leipzig won twice, while also recording zero draws. They endured four defeats in this run, with a scoreline from these matches saying 14 goals conceded and eight scored.
RB Leipzig will be looking for a good result at BayArena, but backing Bayer Leverkusen in current form looks the value bet this coming Sunday.
Top Offers

VIP program. Immediate money withdrawal. Vault feature which makes it easier to control spending.
The “Bet without Risk” Bonus applies exclusively to new players who open a player account at Stake and place the first bet on Sportsbook between $5 and $25. The KYC level2 MUST be verified. Place your first Sports bet and get your money back if your bet is considered “Lost”. The Bonus will be credited within 72 hours after the end of the event and in case your bet is considered lost. T&Cs apply. Gamble Responsibly. GamblingCare.ie. #ad

VIP program. Immediate money withdrawal. Vault feature which makes it easier to control spending.
Bonus only available once to new customers. Min deposit value = $100. Max deposit value = $1000. The 200% bonus will be credited within 24-48 hours of depositing and reviewing the account. The wager attached to the bonus is 40x (deposit + bonus). Bonus can be used across all Sportsbook and Casino games. T&Cs apply. Gamble Responsibly. GamblingCare.ie. #ad
Bayer Leverkusen vs RB Leipzig Stats
- In the last 11 Bayer Leverkusen matches the sum of goals was over 2.5
- In 9 of the last 11 Bayer Leverkusen matches in the Bundesliga, the sum of goals was over 2.5
- In the last 4 Bayer Leverkusen matches the sum of goals was over 3.5
- Bayer Leverkusen have won the last 4 home matches in a row and the sum of goals was over 2.5
- Bayer Leverkusen have won the last 4 home matches in a row while scoring more than 1.5 goals
- In 16 of the last 18 RB Leipzig matches in the Bundesliga, the sum of goals was over 2.5
- In 14 of the last 16 RB Leipzig matches the sum of goals was over 2.5
- In 10 of the last 11 RB Leipzig away matches the sum of goals was over 2.5
- In 8 of the last 10 RB Leipzig away matches the sum of goals was over 3.5
- RB Leipzig have lost 7 of the last 9 away matches while scoring less than 1.5 goals
Bayer Leverkusen vs RB Leipzig Squads
Bayer Leverkusen Squad
The 42-year-old coach of the home team, Carles Martinez, will select the lineup against RB Leipzig from the squad below. The information in the brackets refers to goals scored and matches played in the Bundesliga this season:
Janis Blaswich (0/0), Mark Flekken (0/3), Niklas Lomb (0/0), Edmond Tapsoba (0/3), Facundo Medina (1/3), Guela Doue (0/1), Jarell Quansah (0/3), Loic Bade (0/2), Lucas Vazquez (0/3), Miguel Gutierrez (0/3), Tim Oermann (0/0), Aleix Garcia (0/3), Equi Fernandez (1/3), Ibrahim Maza (1/3), Jonas Hofmann (0/1), Kennet Eichhorn (0/0), Malik Tillman (0/3), Naba Mensah (0/0), Nathan Tella (0/0), Robert Andrich (0/1), Afonso Moreira (0/3), Aleksa Damjanovic (0/0), Christian Kofane (2/3), Eliesse Ben Seghir (0/0), Martin Terrier (0/1), Montrell Culbreath (0/0), Moussa Diaby (0/2), Ndjicoura Bomba (0/0), Patrik Schick (3/3), Victor Okoh Boniface (0/1).
RB Leipzig Squad
Below is the full team squad of RB Leipzig. The manager Demichelis will pick his starting XI against Bayer Leverkusen from these players:
Leopold Zingerle (0/0), Maarten Vandevoordt (0/3), Oerjan Haaskjold Nyland (0/0), Abdoul Kone (0/0), Benjamin Henrichs (0/2), Castello Lukeba (0/2), David Raum (0/3), Hugo Novoa (0/0), Lukas Klostermann (0/0), Max Finkgrafe (0/1), Maxime Esteve (0/2), Willi Orban (1/3), Andrija Maksimovic (0/1), Benno Kaltefleiter (0/0), Christoph Baumgartner (0/0), Ezechiel Banzuzi (0/3), Forzan Assan Ouedraogo (0/1), Neil El Aynaoui (0/2), Nicolas Seiwald (0/2), Ridle Baku (2/3), Rocco Reitz (1/1), Viggo Gebel (0/0), Antonio Nusa (2/3), Brajan Gruda (0/2), Christopher Nkunku (1/3), Johan Bakayoko (0/2), Marc Guiu (0/1), Romulo Cruz (1/1), Samba Konate (0/1), Tidiam Gomis (1/3).
Bayer Leverkusen vs RB Leipzig Team News
Bayer Leverkusen have an almost full squad available against RB Leipzig at BayArena with only one player possibly missing.
Bayer Leverkusen are unable to field Victor Okoh Boniface this coming Sunday against RB Leipzig, as he is sidelined with an injury.
At the time of writing, RB Leipzig just have two players on the injured and absent list, as they prepare for their match on Sunday. Maxime Esteve and Abdoul Kone can't be called upon by RB Leipzig, as they are all sidelined with a suspension.
Bayer Leverkusen vs RB Leipzig Lineups
Bayer Leverkusen vs RB Leipzig H2H
Bayer Leverkusen won the last two meetings against RB Leipzig, as they followed up a 3-1 win by beating their upcoming opponent by a 4-1 score. Bayer Leverkusen have a 6-1-3 advantage over RB Leipzig, whom they beat 4-1, the last time they faced each other. The bookmakers have the hosts to win this match at best price odds of 19/20.
Bayer Leverkusen vs RB Leipzig Results
The past ten matches between Bayer Leverkusen and RB Leipzig have largely been entertaining affairs. Over 2.5 goals came out a winning bet seven times in these encounters. It seems only natural to look for goals this coming Sunday. Over 2.5 goals is best priced at odds of 1/3 with the bookies.
Bayer Leverkusen vs RB Leipzig Betting Tips
As the new Bundesliga campaign has recently started, we are still a bit in the dark, as to which striker will dominate the top scorer table for Bayer Leverkusen and RB Leipzig this season. However, there might be some interesting prospects, when looking at the list of players who are in the best form at the moment.
Bayer Leverkusen claimed all three points seven times in their last 10 home matches across all tournaments, while also drawing one along the way. They endured defeat in two of the games in this run. RB Leipzig won three of their last 10 games away, while drawing zero and losing seven in this series of matches. Bayer Leverkusen should feel good about scoring this coming Sunday, since RB Leipzig managed a clean sheet only once in their previous 10 away games. The hosts fought their way to four clean sheets in their previous 10 matches played at home.
Over 3.5 goals happened seven times in the last ten encounters between these two rivals. Bayer Leverkusen managed an average of 2.2 goals, with RB Leipzig averaging 1.5 goals. Both teams to score was a winning bet seven times in this run of matches. Over 2.5 goals came out nine times in the previous ten matches across all tournaments for Bayer Leverkusen, who scored an average of 2.6 goals along the way. Over 2.5 goals came out in eight of the last 10 matches RB Leipzig played across all tournaments. They managed to score an average of 2.4 goals themselves during this run.