Mainz 05 vs Bayer Leverkusen Betting Odds, Tips, Predictions, Preview 18th October 2025

Bayer Leverkusen go up against Mainz 05 on Saturday for a Bundesliga meeting at MEWA Arena.
Mainz 05 are placed 16th with four points after six matches. Bayer Leverkusen occupy a position as fiveth in the league on 11 points.
Mainz 05 welcome their visitors from Bayer Leverkusen with the aim of closing the gap in the Bundesliga standings. A successful outcome could be crucial for their future endeavours this season.
Mainz 05 only average a modest 1.2 goals per game in their last ten matches in this tournament, in which they scored 12 goals. They also conceded 17 for an average of 1.7 per game. They kept their opponents from scoring zero times.
Bayer Leverkusen show off splendid stats in their last ten matches, where they hit the target two times on average per game. They scored 20 goals and conceded 16, an average of 1.6 a game. They held on for a clean sheet in two of these.
Their latest encounter was a belter of a game, which finished with a 2-2 scoreline. An uncommon result, but we would not mind a similar goal fest this coming Saturday.
Mainz 05 vs Bayer Leverkusen Prediction
Mainz 05 Form
Mainz 05 are currently performing inconsistently, as they lost against Borussia Dortmund by a 0-2 score, before winning 0-1 against Omonia Nicosia. They lost again in their most recent match, this time 4-0 against Hamburger SV. Mainz 05 did not win any of their last six Bundesliga matches at the MEWA Arena. They came through these matches with a record of two draws and three defeats, in which they conceded eight and scored seven goals.
Mainz 05 entered the season dreaming of medals, but find themselves far off track following a lousy run of form.
Bayer Leverkusen Form
Bayer Leverkusen look in good shape before their upcoming match as they seek to remain unbeaten. In their last three matches, they first beat St. Pauli by 1-2, before drawing 1-1 with PSV Eindhoven. They were back as winners last time out, when they took out Union Berlin by a 2-0 scoreline. Bayer Leverkusen claimed two wins against four draws and zero defeats in their last six away matches in the Bundesliga. The scoreline from these matches reads nine goals conceded and 11 scored.
They are one of only a few teams capable of taking the title in the Bundesliga, and Bayer Leverkusen currently remain on course.
Head-to-head encounters tend to bring out the best in both sides, and we fully expect the trend to continue, when Mainz 05 renew Bayer Leverkusen their acquaintance.
Mainz 05 fought their way to zero wins and zero points from their last three games against teams inside the top six. They were on target zero times in these matches, but also let in four goals. Mainz 05 have a record of one win, one draw and four defeats in the Bundesliga this season. Bayer Leverkusen are looking at three wins, two draws and one defeat in the Bundesliga.
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Mainz 05 vs Bayer Leverkusen Stats
- Mainz 05 have lost the last 3 home matches in a row in the Bundesliga while scoring less than 0.5 goals
- Mainz 05 have lost the last 3 home matches in a row in the Bundesliga and the sum of goals was under 2.5
- Mainz 05 have lost the last 3 home matches in a row in the Bundesliga while scoring less than 1.5 goals
- Mainz 05 have lost 3 of the last 4 home matches while scoring less than 0.5 goals
- In 7 of the last 9 Mainz 05 matches the sum of goals was under 3.5
- In 7 of the last 8 Bayer Leverkusen matches in the Bundesliga, the sum of goals was over 2.5
- In 8 of the last 10 Bayer Leverkusen away matches the sum of goals was over 2.5
- In the last 4 Bayer Leverkusen away matches in the Bundesliga, the sum of goals was over 2.5
- In 6 of the last 8 Bayer Leverkusen matches the sum of goals was over 2.5
- In the last 3 Bayer Leverkusen matches the sum of goals was under 3.5
Mainz 05 vs Bayer Leverkusen Squads
Mainz 05 Squad
Henriksen will select the starting XI for the upcoming match against Bayer Leverkusen from the following players (the statistics in the brackets represent goals scored and matches played in the Bundesliga this season):
Daniel Batz (0/0), Lasse Riess (0/2), Robin Zentner (0/5), Andreas Hanche-Olsen (0/6), Anthony Caci (0/4), Danny da Costa (0/6), Kacper Potulski (0/0), Konstantin Schopp (0/0), Lennard Maloney (0/3), Maxim Dal (0/0), Maxim Leitsch (0/2), Phillipp Mwene (0/6), Silvan Widmer (0/4), Stefan Bell (0/6), Daniel Gleiber (0/0), Dominik Kohr (1/5), Jae-Sung Lee (0/4), Jeremiah Debrah (0/0), Kaishu Sano (1/6), Nadiem Amiri (1/6), Niklas Tauer (0/0), Nikolas Veratschnig (0/4), Sota Kawasaki (0/1), Armindo Sieb (1/6), Arnaud Nordin (0/5), Ben Bobzien (0/1), Benedict Hollerbach (0/2), Kasey Bos (0/0), Nelson Weiper (0/6), Paul Nebel (1/4), William Boeving (0/1).
Bayer Leverkusen Squad
Below is the full team squad of Bayer Leverkusen. The manager Hjulmand will pick his starting XI against Mainz 05 from these players:
Janis Blaswich (0/0), Mark Flekken (0/6), Niklas Lomb (0/0), Alejandro Grimaldo (2/6), Arthur (0/2), Axel Tape-Kobrissa (0/4), Edmond Tapsoba (1/6), Jarell Quansah (1/6), Jeanuel Belocian (0/1), Loic Bade (0/5), Lucas Vazquez (0/4), Aleix Garcia (0/6), Claudio Echeverri (0/3), Equi Fernandez (0/3), Exequiel Palacios (0/2), Ibrahim Maza (0/4), Jonas Hofmann (0/3), Malik Tillman (2/5), Nathan Tella (0/3), Robert Andrich (0/5), Alejo Sarco (0/0), Christian Kofane (1/6), Eliesse Ben Seghir (0/2), Ernest Poku (2/5), Ken Izekor (0/0), Martin Terrier (0/0), Patrik Schick (3/5).
Mainz 05 vs Bayer Leverkusen Team News
Mainz 05 could have as few as two players on the injured and absent list for their next assignment on Saturday. Mainz 05 have to alter their line-up, as both Dominik Kohr and Phillipp Mwene get a day in the shade.
Mainz 05 vs Bayer Leverkusen Lineups
Mainz 05 vs Bayer Leverkusen H2H
Supporters will be hoping to see a similarly thrilling encounter, as it turned out to be the last time Mainz 05 played against Bayer Leverkusen. It finished 2-2 in a great match between the pair. All in all, Bayer Leverkusen have a fine reading on Mainz 05 in previous seasons with a 6-2-2 advantage going into this match. The bookies have Bayer Leverkusen to win this match at best price odds of 23/17.
Mainz 05 vs Bayer Leverkusen Results
Entertainment seems close to guaranteed when Mainz 05 welcome Bayer Leverkusen as over 2.5 goals came out a winning bet seven times in ten matches. Over 2.5 goals is best priced at odds of 8/11 with the bookies this coming Saturday.
Mainz 05 vs Bayer Leverkusen Betting Tips
Armindo Sieb is the most prolific Bundesliga marksman for the home team, scoring twice recently. Bayer Leverkusen look to Patrik Schick, hoping he can add to his current total of three Bundesliga goals in his latest games.
Mainz 05 claimed a modest two wins from their previous 10 home matches across all tournaments. They split the points with the visiting team in five of the games, whilst losing three. Bayer Leverkusen won four of their last 10 games away, drew four and lost two of the games in this run. Both teams have been poor at keeping their opponents from scoring in their last 10 games, respectively. Mainz 05 managed a clean sheet in two of their games at home, Bayer Leverkusen kept a clean sheet in two of their last 10.
Over 2.5 goals came out seven times in the last ten encounters between these two teams. Mainz 05 managed an average of 1.1 goals, with Bayer Leverkusen averaging 1.9 goals in these. Both teams to score was a winning bet five times in this run of matches. Over 2.5 goals happened in four of Mainz 05’s last ten matches across all tournaments. They pulled off an average of 1.2 goals during this run. In the last ten games for Bayer Leverkusen, six of them had more than 2.5 goals, and they scored an average of 1.9 times goals per game themselves.