Mainz 05 vs Hoffenheim Betting Odds, Tips, Predictions, Preview 21st November 2025

Hoffenheim go up against Mainz 05 this coming Friday for a Bundesliga meeting at MEWA Arena.
Placed 17th in the table Mainz 05 have amassed five points after ten matches. On 19 points, Hoffenheim rank sixth with ten matches played this season.
With four wins on the bounce, Hoffenheim are ready to take on anyone, and motivation should be high to let Mainz 05 be the next victim in line.
Mainz 05 go into their next Bundesliga match, scoring a humble average of one per game in their last ten matches. They scored a mundane ten times, while conceding 18. That amounts to an average of 1.8 per game, where they kept their opponents from scoring zero times.
Hoffenheim are brimming with confidence in front of goal before the upcoming away match in the Bundesliga, as they can show off very handsome numbers from their previous ten games. The visitors scored 2.1 times on average per match, for a total of 21 goals. They also let in 16 goals, leaving an average of 1.6 per match. They fought their way to one clean sheets.
Mainz 05 were defeated by 2-0 in their last encounter with Hoffenheim, but did win the reverse match 2-0, though.
Mainz 05 vs Hoffenheim Prediction
Mainz 05 Form
Mainz 05 have seen it all in their last three matches, which added four points to their account. They first shared the points in a 1-1 draw with Werder Bremen, before claiming 3 points in a 2-1 win against Fiorentina. Unfortunately for them, this was followed by a 1-0 defeat at the hands of Eintracht Frankfurt. Mainz 05 didn't manage a single win in any of their previous six Bundesliga games at the MEWA Arena. They have a record of two draws and four defeats, in which they conceded 11 and scored six goals.
Mainz 05 entered the season hunting for a title, however they find themselves far off track at this stage.
Hoffenheim Form
Hoffenheim look well suited to take on any opponent as their last three matches ended with a draw and two wins. They started off drawing 1-1 with St. Pauli, before downing first Wolfsburg by 2-3, then RB Leipzig in a 3-1 win. Hoffenheim recorded a very decent outcome of four wins from six away matches in the Bundesliga, in which they banged in 15 goals, whilst conceding eight. They remained undefeated, but did draw twice.
Ambitions are high for Hoffenheim, and winning the title is still possible, but they need to raise their level to achieve the highest prize.
Though favourites for the win, we are uncertain the current form of Mainz 05 backs this claim. We believe there is good value in Hoffenheim, perhaps with the backing of the draw.
Mainz 05 fought their way to zero wins and zero points from their last four games against teams inside the top six. They were on target four times in these matches, but also let in nine goals. Hoffenheim won three of their previous three encounters with opponents from the bottom six of the Bundesliga. They scored nine and conceded three goals and collected nine points. Mainz 05 have so far been able to win just once after ten Bundesliga games played, in stead showing off two draws and seven defeats. Hoffenheim have a record of six wins, one draw and three defeats in the Bundesliga.
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Mainz 05 vs Hoffenheim Stats
- In the last 6 Mainz 05 matches the sum of goals was under 3.5
- In 8 of the last 10 Mainz 05 home matches the sum of goals was under 3.5
- In 4 of the last 5 Mainz 05 home matches in the Bundesliga, the sum of goals was under 2.5
- In 5 of the last 7 Mainz 05 home matches the sum of goals was under 2.5
- In the last 3 Mainz 05 matches in the Bundesliga, the sum of goals was under 3.5
- In 15 of the last 17 Hoffenheim away matches the sum of goals was over 2.5
- Hoffenheim have won the last 5 matches in a row while scoring more than 2.5 goals
- Hoffenheim have won 11 of the last 13 away matches and the sum of goals was over 2.5
- Hoffenheim have won 11 of the last 13 away matches while scoring more than 1.5 goals
- In 13 of the last 15 Hoffenheim matches in the Bundesliga, the sum of goals was over 2.5
Mainz 05 vs Hoffenheim Squads
Mainz 05 Squad
The 50-year-old coach of the home team, Bo Henriksen, will select the lineup against Hoffenheim from the squad below. The information in the brackets refers to goals scored and matches played in the Bundesliga this season:
Daniel Batz (0/0), Lasse Riess (0/3), Robin Zentner (0/8), Andreas Hanche-Olsen (0/9), Anthony Caci (0/4), Danny da Costa (0/10), Kacper Potulski (0/0), Konstantin Schopp (0/0), Lennard Maloney (0/5), Maxim Dal (0/0), Maxim Leitsch (0/2), Phillipp Mwene (0/10), Silvan Widmer (1/7), Stefan Bell (0/8), Daniel Gleiber (0/0), Dominik Kohr (1/9), Jae-Sung Lee (1/8), Jeremiah Debrah (0/0), Kaishu Sano (1/10), Nadiem Amiri (3/10), Niklas Tauer (0/0), Nikolas Veratschnig (0/8), Sota Kawasaki (0/2), Armindo Sieb (2/10), Arnaud Nordin (0/8), Ben Bobzien (0/1), Benedict Hollerbach (0/6), Kasey Bos (0/0), Nelson Weiper (0/9), Paul Nebel (1/8), William Boeving (0/2).
Hoffenheim Squad
Below is the full team squad of Hoffenheim. The manager Ilzer will pick his starting XI against Mainz 05 from these players:
Luca Philipp (0/0), Lukas Petersson (0/0), Oliver Baumann (0/10), Albian Hajdari (1/8), Arthur Chaves (0/4), Bernardo (0/10), Kelven Frees (0/0), Kevin Akpoguma (0/2), Koki Machida (0/1), Ozan Kabak (0/4), Robin Hranac (0/10), Valentin Gendrey (0/0), Vladimir Coufal (1/10), Alexander Prass (0/10), Dennis Geiger (0/0), Grischa Proemel (4/10), Hennes Behrens (0/0), Leon Avdullahu (0/10), Muhammed Mehmet Damar (0/7), Umut Tohumcu (0/4), Wouter Burger (2/9), Adam Hlozek (0/0), Andrej Kramaric (3/10), Bazoumana Toure (1/10), David Mokwa (0/0), Fisnik Asllani (5/10), Ihlas Bebou (0/6), Max Moerstedt (0/6), Mergim Berisha (0/0), Tim Lemperle (4/9).
Mainz 05 vs Hoffenheim Team News
Mainz 05 could have as few as two players on the injured and absent list for their next assignment on Friday. Mainz 05 have to alter their line-up, as both Dominik Kohr and Phillipp Mwene get a day in the shade.
Mainz 05 vs Hoffenheim Lineups
Mainz 05 vs Hoffenheim H2H
Mainz 05 were defeated by 2-0 in their last encounter with Hoffenheim, but did win the reverse match 2-0, though. Mainz 05 hold a 6-2-2 advantage against Hoffenheim from their latest encounters. The bookies best betting odds on a home win are at 5/4.
Mainz 05 vs Hoffenheim Results
Over 2.5 goals happened only three times in the last ten matches Mainz 05 took on Hoffenheim. Under 2.5 goals is best priced at odds of 13/10 with the bookies.
Mainz 05 vs Hoffenheim Betting Tips
Nadiem Amiri is the most prolific Bundesliga marksman for the home team, scoring twice recently. Hoffenheim look to Grischa Proemel, hoping he can add to his current total of three Bundesliga goals in his latest games.
Mainz 05 claimed three wins, drew two and lost five of their previous 10 home matches across all tournaments. Hoffenheim won eight, drew two and lost zero of their last 10 games away. Hoffenheim claimed five wins without conceding a goal from their last 10 outings away from home. A number worth bearing in mind for an accumulator, depending on your betting strategy.
Less than 2.5 goals came out three times in the past ten encounters between these two while both teams not to score was a winning bet five times. Mainz 05 managed an average of 1.6 goals, with Hoffenheim averaging one goal. Over 2.5 goals happened in four of Mainz 05’s last ten matches across all tournaments. They pulled off an average of 0.9 goals during this run. Over 2.5 goals appeared in eight of the last ten matches that Hoffenheim played across all tournaments. They scored 2.1 times on average in the process.