Mainz 05 vs RB Leipzig Betting Odds, Tips, Predictions, Preview 13th September 2025

As the early season favourites, Mainz 05 will look to justify their title credentials on Saturday when they take on RB Leipzig for a round 3 match in the Bundesliga.

A look at the Bundesliga standings shows that two points and two places currently separate the two teams.

Mainz 05 will be feeling the pressure of securing a first win of the season in the Bundesliga after collecting a modest one point in the first couple of rounds.

Nobody likes to be on the losing side, especially so early into a new season. Mainz 05 and RB Leipzig are no exception in this respect. Both teams are eager to improve from last term, leading us to expect an exciting affair at MEWA Arena.

Mainz 05 go into their next Bundesliga match, scoring a humble average of 1.2 per game in their last ten matches. They scored a mundane 12 times, while conceding 17. That amounts to an average of 1.7 per game, where they kept their opponents from scoring zero times.

RB Leipzig scored 14 goals, conceded 21 and managed two clean sheets in their previous ten matches.

Mainz 05 beat RB Leipzig by 2-1 in their most recent match, while RB Leipzig claimed a 2-0 win in the match prior to that.

Mainz 05 vs RB Leipzig Prediction

Mainz 05 Form

Mainz 05 have seen it all in their last three matches. Against FC Koln, they came out empty-handed in a 0-1 defeat, whereafter they avenged themselves in a 4-1 win against Rosenborg. Their latest match saw them sharing the spoils in a 1-1 draw against Wolfsburg. Mainz 05 are without a win in their last six Bundesliga matches on home soil, which produced a record of five draws and one defeats, in which they conceded nine and scored eight goals.

RB Leipzig Form

Two victories are what RB Leipzig have to show from their past three matches, as they first beat Sandhausen 2-4. This was followed by a 6-0 defeat against Bayern Munich, before winning again 2-0 against FC Heidenheim. RB Leipzig only have one paltry win to show from the last six away games in the Bundesliga. In these six matches they drew two and lost three as well as being outscored by 13 goals to three.

RB Leipzig will be looking for a good result at MEWA Arena, but backing Mainz 05 in current form looks the value bet this coming Saturday.

Mainz 05 vs RB Leipzig Squads

Mainz 05 Squad

The 50-year-old coach of the home team, Bo Henriksen, will select the lineup against RB Leipzig from the squad below. The information in the brackets refers to goals scored and matches played in the Bundesliga this season:

Daniel Batz (0/0), Lasse Riess (0/0), Robin Zentner (0/2), Andreas Hanche-Olsen (0/2), Anthony Caci (0/2), Danny da Costa (0/2), Konstantin Schopp (0/0), Lennard Maloney (0/1), Maxim Dal (0/0), Maxim Leitsch (0/0), Phillipp Mwene (0/2), Silvan Widmer (0/1), Stefan Bell (0/2), Daniel Gleiber (0/0), Dominik Kohr (0/2), Jae-Sung Lee (0/2), Kaishu Sano (0/2), Nadiem Amiri (1/2), Niklas Tauer (0/0), Nikolas Veratschnig (0/1), Sota Kawasaki (0/0), Armindo Sieb (0/2), Arnaud Nordin (0/1), Ben Bobzien (0/1), Benedict Hollerbach (0/1), Kasey Bos (0/0), Nelson Weiper (0/2), Paul Nebel (0/1).

RB Leipzig Squad

Here is the full team squad of RB Leipzig. The 37 year-old Ole Werner will select his starting lineup from the following players:

Leopold Zingerle (0/0), Maarten Vandevoordt (0/0), Peter Gulacsi (0/2), Benjamin Henrichs (0/0), Castello Lukeba (0/2), David Raum (0/2), El Chadaille Bitshiabu (0/0), Hugo Novoa (0/0), Kosta Nedeljkovic (0/1), Lukas Klostermann (0/0), Lutsharel Geertruida (0/0), Max Finkgrafe (0/0), Willi Orban (0/2), Amadou Haidara (0/0), Andrija Maksimovic (0/0), Antonio Nusa (0/2), Christoph Baumgartner (1/2), Eljif Elmas (0/0), Ezechiel Banzuzi (0/2), Forzan Assan Ouedraogo (0/2), Kevin Kampl (0/0), Nicolas Seiwald (0/2), Ridle Baku (0/2), Viggo Gebel (0/0), Xaver Schlager (0/2), Ikoma Lois Openda (0/2), Johan Bakayoko (0/2), Robert Ramsak (0/0), Romulo Cruz (1/2), Tidiam Gomis (0/0), Timo Werner (0/0), Yan Diomande (0/2).

Mainz 05 vs RB Leipzig Team News

Mainz 05 could have as few as two players on the injured and absent list for their next assignment this coming Saturday. Dominik Kohr and Phillipp Mwene can't be called up by the Mainz 05-manager, with both serving a ban.

Mainz 05 vs RB Leipzig Lineups

Mainz 05 vs RB Leipzig H2H

Mainz 05 beat RB Leipzig by 2-1 in their most recent match, while RB Leipzig claimed a 2-0 win in the match prior to that. Mainz 05 were a little more successful than RB Leipzig in recent meetings, and go into their next encounter with a 5-2-3 advantage. Naturally, betting on Mainz 05 has more often than not proved the profitable way to go. The bookies best betting odds on a home win are at 7/5.

Mainz 05 vs RB Leipzig Results

In the last ten matches between Mainz 05 and RB Leipzig over 2.5 goals came out five times. Odds on at least three goals are at 2/3 with bookies.

Mainz 05 vs RB Leipzig Betting Tips

Nadiem Amiri found the target two times in his previous six matches, whereas Lukas Klostermann just scored once in a similar number of matches.

Mainz 05 won three of the previous 10 home matches across all tournaments, while drawing six and losing one as well. RB Leipzig won four from a possible 10 away from home, as they also drew one and lost five in this run. Strap yourselves up for a goals at MEWA Arena since both teams scored in six of the last 10 home matches for Mainz 05. The same occurred in five of the last 10 league games away from home for RB Leipzig.

Over 2.5 goals was a winning bet five times in the past ten encounters between Mainz 05 and RB Leipzig, with the latter scoring 1.3 goals on average in these. Mainz 05 managed an average of 1.4 goals as both teams scored five times in this run. Over 2.5 goals happened in five of Mainz 05’s last ten matches across all tournaments. They pulled off an average of two goals during this run. Over 2.5 goals were scored in eight of the ten most recent games across all tournaments for RB Leipzig. They performed an average of 2.3 goals in these.