Manchester City vs Southampton Betting Odds, Tips, Predictions, Preview 25th April 2026

Manchester City enjoy home advantage, when visitors Southampton swing by on Saturday for a clash in the FA Cup. The former will be looking to make that home advantage count.

Manchester City took down Southampton in their most recent meeting, and bookmakers deem another win for the home side a likely scenario this coming Saturday.

Manchester City arrive at their next FA Cup match, averaging a sensational 3.6 goals per game in their last ten matches in which, they scored a delicious total of 36 goals, while also conceding six. That amounts to an average of 0.6 per game in which, they kept their opponents from scoring four times.

When it comes to goal-scoring Southampton are not the most prolific side. They scored a sustainable 19 times in their previous ten matches, making it 1.9 goals per game. They conceded nine goals for an average of 0.9 a game, achieving a clean sheet in four of these matches.

Manchester City last faced Southampton on 20 March 2022 at St. Mary's Stadium, when Manchester City scored a 4-1 win.

Manchester City vs Southampton Prediction

Manchester City Form

Manchester City are enjoying their football currently with three wins on the bounce, and it began with a 0-3 win against Chelsea. They went on to beat Arsenal by 2-1, before also getting the better of Burnley in a 0-1 victory. Manchester City have been in potent form at a neutral venue, winning no less than five of the past six FA Cup matches here. They also hammered in 28 goals, while letting in four as they also lost once.

Southampton Form

Southampton look well suited to take on any opponent presently, as their last three matches saw them gaining two victories and a draw. They ran out 3-0 and 1-2 winners against Blackburn and Swansea, respectively. Their winning streak came to an end against Bristol City, as the match resulted in a 2-2 draw. Southampton came through their last six away games in the FA Cup with four wins. Of those six matches, they drew once and lost once in which, they scored ten and conceded nine.

We'd be flabbergasted to see Manchester City waste away a win against Southampton, who could be in for a battering, the way goals have been flowing lately.

Manchester City vs Southampton Squads

Manchester City Squad

Pep Guardiola will choose the starting lineup for the upcoming game against Southampton from the following players:

Gianluigi Donnarumma, James Trafford, Marcus Bettinelli, Abdukodir Khusanov, John Stones, Josko Gvardiol, Marc Guehi, Max Alleyne, Nathan Ake, Rayan Ait Nouri, Rico Lewis, Ruben Dias, Bernardo Silva, Jeremy Doku, Mateo Kovacic, Matheus Nunes, Nico Gonzalez, Nico O'Reilly, Phil Foden, Rayan Cherki, Rodri, Ryan McAidoo, Savinho, Sverre Halseth Nypan, Tijjani Reijnders, Antoine Semenyo, Erling Haaland, Omar Marmoush.

Southampton Squad

Below is the full team squad of Southampton. The manager Eckert will pick his starting XI against Manchester City from these players:

McCarthy, Peretz, Long, Jones, Jelert, Stephens, Bree, Robinson, Quarshie, Roerslev, Wood, Harwood-Bellis, Welington, Williams, Bragg, Jander, Azaz, Downes, Matsuki, Romeu, Manning, Edozie, Charles, Archer, Larin, Scienza, Oyekunle, Stewart, Fellows.

Manchester City vs Southampton Team News

Manchester City just have a single unavailable player for squad selection, when facing Southampton at a neutral venue.

Rodri sit this one out for Manchester City due to an injury.

Manchester City vs Southampton Lineups

Manchester City vs Southampton H2H

The last time Manchester City faced off against Southampton, The Citizens claimed a 4-1 win at St. Mary's Stadium. The home side were in awesome shape, the last time they played Southampton, as the latter got taught a lesson in a 4-1 win for a high-flying Manchester City team. The bookies have Manchester City to win this match at best price odds of 1/6.

Manchester City vs Southampton Results

The scenario of both teams to score came out two times in the last two matches between Manchester City and Southampton.

Manchester City vs Southampton Betting Tips

Ross Stewart shows decent form right now for Southampton, as he scored two goals in his last six games in the FA Cup. The visitors need more from him, though, when facing Manchester City, who are strong favourites on Saturday. Siding with Erling Haaland also look a nice prospect as he scored three goals in his last six FA Cup matches.

Manchester City won eight of the previous 10 home matches across all tournaments, while drawing one and losing one as well. Southampton won eight from a possible 10 away from home, as they also drew two and lost zero in this run. Manchester City managed to open the scoring in no less than nine of their previous 10 league games on home soil. The visitors from Southampton have been equally ready from the first whistle, scoring the opener in seven of their last 10 away games.

Over 2.5 goals came out two times in the last two encounters between these two teams. Manchester City managed an average of 3.5 goals, with Southampton averaging one goal in these games. Both teams to score was a winning bet two times in this run of matches. Over 2.5 goals came out seven times in the previous ten matches across all tournaments for Manchester City, who scored an average of 1.9 goals along the way. Of the last ten games for Southampton, seven had more than 2.5 goals, while they managed to score an average of 2.2 times goals per game.